CBX5 Antikörper (AA 1-191)

Produktnummer ABIN7868332

Der Maus Monoklonal anti-CBX5 Antikörper (Klon 8G6) (ABIN7868332) detektiert spezifisch CBX5 in WB, IF, FACS und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für CBX5 Antikörper (AA 1-191) (ABIN7868332)

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CBX5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 8G6

Produktdetails anti-CBX5 Antikörper

Bindungsspezifität: AA 1-191

Verwendungszweck: CBX5 Antibody / HP1A / HP1 alpha

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-S191) was used as the immunogen for the CBX5 antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CBX5 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the CBX5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu CBX5

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Andere Bezeichnung: CBX5

Hintergrund: This gene encodes the highly conserved nonhistone protein Chromobox protein homolog 5, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

UniProt: P45973