Centrin 1 Antikörper (AA 1-172)

Produktnummer ABIN7868249

Dieser Maus Monoklonal Antikörper detektiert spezifisch Centrin 1 in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Centrin 1 Antikörper (AA 1-172) (ABIN7868249)

Target: Centrin 1 (CETN1) (Centrin, EF-Hand Protein, 1 (CETN1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Centrin 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: CETN1-9880

Produktdetails anti-Centrin 1 Antikörper

Bindungsspezifität: AA 1-172

Verwendungszweck: Centrin 1 Antibody / CETN1

Aufreinigung: Protein A/G affinity

Immunogen: A portion of amino acids 1-172 from human CETN1 protein was used as the immunogen for the Centrin 1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Centrin 1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Centrin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Centrin 1

Target: Centrin 1 (CETN1) (Centrin, EF-Hand Protein, 1 (CETN1))

Andere Bezeichnung: Centrin 1

Hintergrund: EF-hand type Ca2+-binding proteins consists of several family members, including Centrin-1, Centrin-2 and Centrin-3. The Centrin proteins are ubiquitously expressed cytoskeletal components that show increased expression during cell differentiation. Tissues where cilia are present, such as the retina and testis, express both Centrin-1 and -2, but Centrin-2 is also expressed in nondifferentiated, nonciliated retinal cells (retinoblastoma cells), liver, skeletal muscle, and cardiac muscle. In these tissues, Centrin associates with the centrosomes, mitotic spindle poles, and basal bodies. Knockdown studies reveal a requirement for Centrin in centriole duplication and organization of spindle pole morphology and the completion of cytokinesis. Centrin-3 plays a role in centrosome reproduction.

UniProt: Q12798