Centrin 1 Antikörper (AA 1-172)

Produktnummer ABIN7868244

Der Maus Monoklonal anti-Centrin 1 Antikörper wird verwendet zum Nachweis von Centrin 1 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Centrin 1 Antikörper (AA 1-172) (ABIN7868244)

Target: Centrin 1 (CETN1) (Centrin, EF-Hand Protein, 1 (CETN1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Centrin 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: CETN1-9878

Produktdetails anti-Centrin 1 Antikörper

Bindungsspezifität: AA 1-172

Verwendungszweck: CETN1 Antibody / Centrin 1 (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A portion of amino acids 1-172 from human CETN1 protein was used as the immunogen for the CETN1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CETN1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CETN1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Centrin 1

Target: Centrin 1 (CETN1) (Centrin, EF-Hand Protein, 1 (CETN1))

Andere Bezeichnung: CETN1

Hintergrund: EF-hand type Ca2+-binding proteins consists of several family members, including Centrin-1, Centrin-2 and Centrin-3. The Centrin proteins are ubiquitously expressed cytoskeletal components that show increased expression during cell differentiation. Tissues where cilia are present, such as the retina and testis, express both Centrin-1 and -2, but Centrin-2 is also expressed in nondifferentiated, nonciliated retinal cells (retinoblastoma cells), liver, skeletal muscle, and cardiac muscle. In these tissues, Centrin associates with the centrosomes, mitotic spindle poles, and basal bodies. Knockdown studies reveal a requirement for Centrin in centriole duplication and organization of spindle pole morphology and the completion of cytokinesis. Centrin-3 plays a role in centrosome reproduction.

UniProt: Q12798