SIVA1 Antikörper (AA 1-141)

Produktnummer ABIN7868145

Der Kaninchen Polyklonal anti-SIVA1 Antikörper wird verwendet zum Nachweis von SIVA1 in Proben von Human. Er wurde validiert für WB, ELISA und FACS.

Kurzübersicht für SIVA1 Antikörper (AA 1-141) (ABIN7868145)

Target: SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIVA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-SIVA1 Antikörper

Bindungsspezifität: AA 1-141

Verwendungszweck: SIVA1 Antibody / CD27BP

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids M1-T141) was used as the immunogen for the SIVA1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SIVA1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the SIVA1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu SIVA1

Target: SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))

Andere Bezeichnung: SIVA1

Hintergrund: Apoptosis regulatory protein Siva is a protein that in humans is encoded by the SIVA1 gene. This gene encodes an E3 ubiquitin ligase that regulates cell cycle progression, cell proliferation and apoptosis. The N-terminus of this protein binds to the cytoplasmic tail of the CD27 antigen, a member of the tumor necrosis factor receptor (TNFR) superfamily. In response to UV radiation-induced DNA damage, this protein has been shown to mediate the ubiquitination of proliferating cell nuclear antigen (PCNA), an important step in translesion DNA synthesis.

UniProt: O15304

Pathways: Positive Regulation of Endopeptidase Activity