BATF3 Antikörper (AA 1-123)

Produktnummer ABIN7868023

Der Maus Monoklonal anti-BATF3 Antikörper (Klon PCRP-BATF3-1E5) (ABIN7868023) detektiert spezifisch BATF3 in IHC (p) und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für BATF3 Antikörper (AA 1-123) (ABIN7868023)

Target: BATF3 (Basic Leucine Zipper Transcriptional Factor ATF-Like 3 (BATF3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BATF3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Klon: PCRP-BATF3-1E5

Produktdetails anti-BATF3 Antikörper

Bindungsspezifität: AA 1-123

Verwendungszweck: SNFT Antibody / BATF3

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-123) from the human protein was used as the immunogen for the SNFT antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SNFT antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the SNFT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu BATF3

Target: BATF3 (Basic Leucine Zipper Transcriptional Factor ATF-Like 3 (BATF3))

Andere Bezeichnung: SNFT

Hintergrund: SNFT, also known as BATF3 (basic leucine zipper transcription factor, ATF-like 3), JUNDM1 or JDP1, is a 127 amino acid protein that localizes to the nucleus and contains one bZIP domain. Interacting with c-Jun, SNFT functions as a negative regulator of AP-1-mediated transcription, specifically by heterodimerizing with c-Jun and binding to DNA response elements. The gene encoding SNFT maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

UniProt: Q9NR55