Fission 1 Antikörper (AA 1-121)

Produktnummer ABIN7868019

Der Kaninchen Polyklonal anti-Fission 1 Antikörper wird verwendet zum Nachweis von Fission 1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IF, IHC (p) und FACS.

Kurzübersicht für Fission 1 Antikörper (AA 1-121) (ABIN7868019)

Target: Fission 1 (FIS1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fission 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-Fission 1 Antikörper

Bindungsspezifität: AA 1-121

Verwendungszweck: TTC11 Antibody / FIS1

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids M1-D121) was used as the immunogen for the FIS1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the FIS1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the FIS1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Fission 1

Target: Fission 1 (FIS1)

Andere Bezeichnung: TTC11

Hintergrund: Mitochondrial fission 1 protein (FIS1) is a protein that in humans is encoded by the FIS1 gene on chromosome 7. It is mapped to 7q22.1. The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission. Its role in mitochondrial fission thus implicates it in the regulation of mitochondrial morphology, the cell cycle, and apoptosis. By extension, the protein is involved in associated diseases, including neurodegenerative diseases and cancers.

UniProt: Q9Y3D6

Pathways: Positive Regulation of Endopeptidase Activity