alpha KGDHC Antikörper (AA 1-1023)

Produktnummer ABIN7867921

Der Kaninchen Polyklonal anti-alpha KGDHC Antikörper (ABIN7867921) detektiert spezifisch alpha KGDHC in WB, ELISA und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für alpha KGDHC Antikörper (AA 1-1023) (ABIN7867921)

Target: alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser alpha KGDHC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-alpha KGDHC Antikörper

Bindungsspezifität: AA 1-1023

Verwendungszweck: OGDH Antibody / 2-oxoglutarate dehydrogenase

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids M1-S1023) was used as the immunogen for the OGDH antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the OGDH antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the OGDH antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu alpha KGDHC

Target: alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))

Andere Bezeichnung: OGDH

Hintergrund: Alpha-ketoglutarate dehydrogenase also known as 2-oxoglutarate dehydrogenase E1 component, mitochondrial is an enzyme that in humans is encoded by the OGDH gene. This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[

UniProt: Q02218