CD43 Antikörper (PE)

Produktnummer ABIN7867432

Der PE-konjugierte Kaninchen Monoklonal anti-CD43 Antikörper (Klon DM211) (ABIN7867432) detektiert spezifisch CD43 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CD43 Antikörper (PE) (ABIN7867432)

Target: CD43 (SPN) (Sialophorin (SPN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CD43 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: DM211

Produktdetails anti-CD43 Antikörper (PE)

Verwendungszweck: PE-conjugated Anti-CD43 antibody(DM211), Rabbit mAb

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cyt 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2°C-8°C for 6 months

Haltbarkeit: 6 months

Details zu CD43

Target: CD43 (SPN) (Sialophorin (SPN))

Andere Bezeichnung: CD43

Hintergrund:

Synonyms: CD43, GALGP, GPL115, LSN

Target Background: This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]

UniProt: P16150

Pathways: Regulation of Leukocyte Mediated Immunity