Rekombinanter SELPLG Antikörper (PE)
Kurzübersicht für Rekombinanter SELPLG Antikörper (PE) (ABIN7867426)
Target
Alle SELPLG Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- PE-conjugated Anti-CD162 antibody(DMC283), IgG1 Chimeric mAb
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Aufreinigung
- Purified from cell culture supernatant by affinity chromatography
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Isotyp
- IgG1
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Applikationshinweise
- Flow Cyt 1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid PBS with 0.05 % Proclin300, 1 % BSA
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2°C-8°C for 6 months
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Haltbarkeit
- 6 months
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- SELPLG (Selectin P Ligand (SELPLG))
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Andere Bezeichnung
- SELPLG
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Hintergrund
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Synonyms: PSGL-1,PSGL1,CD162,SELPLG,Selectin P ligand
Target Background: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
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UniProt
- Q14242
Target
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