Rekombinanter FOLR2 Antikörper (PE)

Produktnummer ABIN7867270

Der PE-konjugierte Kaninchen Chimeric anti-FOLR2 Antikörper (Klon DMC390) (ABIN7867270) detektiert spezifisch FOLR2 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter FOLR2 Antikörper (PE) (ABIN7867270)

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser FOLR2 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: DMC390

Produktdetails anti-FOLR2 Antikörper (PE)

Verwendungszweck: PE-conjugated Anti-FOLR2 antibody(DMC390), IgG1 Chimeric mAb

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cyt 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2°C-8°C for 6 months

Haltbarkeit: 6 months

Details zu FOLR2

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Andere Bezeichnung: FOLR2

Hintergrund:

Synonyms: BETA-HFR, FBP, FBP:PL-1, FOLR1, FR-BETA, FR-P3, FRbeta

Target Background: The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.

UniProt: P14207

Pathways: Dicarboxylic Acid Transport