SOX2 Antikörper

Produktnummer ABIN7865738

Dieser Maus Monoklonal Antikörper detektiert spezifisch SOX2 in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SOX2 Antikörper (ABIN7865738)

Target: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SOX2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: IHC665

Produktdetails anti-SOX2 Antikörper

Verwendungszweck: anti-SOX-2 mouse monoclonal, IHC665, purified

Aufreinigung: affinity chromatography

Immunogen: Recombinant Human SOX-2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optional[ICC/IF_dilution]: 1:50-1:200 (microwave treatment recommended)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Tris pH 7.3-7.7 with 1 % BSA and 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: store at 2 - 8 °C

Details zu SOX2

Target: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Andere Bezeichnung: SOX-2

Hintergrund: SOX2, also known as SRY (Sex Determining Region Y)-Box 2, is a transcription factor that acts to regulate pluripotency of undifferentiated embryonic stem cells, and to regulate gene expression in the stomach. This diagnostic grade SOX2 IVD antibody is used to detect melanoma, testicular germ cell tumour, cervical carcinoma, lung cancer, breast cancer with basal cell phenotype, and teratoma of the central nervous system. SOX2 has been reported as a predictor of poor outcome in stage I lung adenocarcinomas. Anti-SOX2 is also used to recognize squamous cell carcinomas of the lung and gastrointestinal tract, and may be useful for detecting embryonal carcinoma.

Pathways: Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis