CD16 Antikörper
Kurzübersicht für CD16 Antikörper (ABIN7865576)
Target
Alle CD16 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Verwendungszweck
- anti-CD16 mouse monoclonal, ICO-116, purified
-
Aufreinigung
- affinity chromatography
-
Immunogen
- human PBL
-
Isotyp
- IgG1 kappa
-
-
-
-
Applikationshinweise
-
ICC/IF_dilution: 1:100-1:200 (0.5-1.0 μg/mL)
FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml
IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 100 μg/mL
-
Buffer
- PBS with 0.02 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Informationen zur Lagerung
- store at 2 - 8 °C
-
-
- CD16
-
Andere Bezeichnung
- CD16
-
Hintergrund
- ICO-116 specifically recognizes CD16. This molecule also named low affinity Fc receptor for IgG (FcgammaRIII) exhibits two truncated Ig-like domains and is 50-80 kDa. It is highly expressed on NK-cells, granulocytes and macrophages. ICO-116 binds to 15 % peripheral lymphocytes of healthy donors (NK-cells), granulocytes, macrophages. CD16 represents the functional receptor structure for antibody-dependent cellular cytotoxicity. Positive control: K-562 or U-937 cells. Lymph nodes and tonsils.
-
Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
-