OPRL1 Antikörper

Produktnummer ABIN7862541

Der Kaninchen Polyklonal anti-OPRL1 Antikörper wird verwendet zum Nachweis von OPRL1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für OPRL1 Antikörper (ABIN7862541)

Target: OPRL1 (Opiate Receptor-Like 1 (OPRL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPRL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-OPRL1 Antikörper

Verwendungszweck: Rabbit Anti-OPRX Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of OPRX protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human OPRX protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu OPRL1

Target: OPRL1 (Opiate Receptor-Like 1 (OPRL1))

Andere Bezeichnung: OPRX

Hintergrund: Nociceptin receptor, Kappa-type 3 opioid receptor, KOR-3, Orphanin FQ receptorThe protein encoded by OPRL1 is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. A promoter region between OPRL1 and the 5'-adjacent RGS19 (regulator of G-protein signaling 19) gene on the opposite strand functions bi-directionally as a core-promoter for both genes, suggesting co-operative transcriptional regulation of these two functionally related genes. Alternatively spliced transcript variants have been described for OPRL1. A recent study provided evidence for translational readthrough in OPRL1 and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Molekulargewicht: 40kD

Gen-ID: 4987

UniProt: P41146