Hepatocyte Specific Antigen Antikörper
Kurzübersicht für Hepatocyte Specific Antigen Antikörper (ABIN7865518)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Hepatocyte Specific Antigen (Hepatocellular Marker) Antibody
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Spezifität
- Hepatocyte Specific Antigen, also called Hepatocyte Paraffin 1 or HepPar1, localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC's occur primarily in the stomach, but they are also found in many other organs. The Hepatocyte Specific Antigen may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of the Hepatocyte Specific Antigen correlates with smaller tumor size and longer patient survival. Occasionally, Hepatocyte Specific Antigen is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
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Aufreinigung
- Ab purified from Bioreactor Concentrate by Protein G.
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Immunogen
- Extract of a formalin-fixed, rejected-allograft of a human liver
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- Hepatocyte Specific Antigen (HepPar-1)
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Andere Bezeichnung
- Hepatocyte Specific Antigen
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Hintergrund
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Not Known
Liver: Virtually all hepatocytes should show an at least moderate granular cytoplasmic staining.
Target
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