Rekombinanter Elastin Antikörper

Produktnummer ABIN7865516

Der Kaninchen Monoklonal anti-Elastin Antikörper (Klon MSVA-648R) (ABIN7865516) detektiert spezifisch Elastin in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter Elastin Antikörper (ABIN7865516)

Target: Elastin (ELN)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Elastin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: MSVA-648R

Produktdetails anti-Elastin Antikörper

Expressionssystem: HEK-293 Cells

Verwendungszweck: Recombinant Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) Antibody

Spezifität: Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries.It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticityto the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.

Aufreinigung: Ab produced in HEK293 cell mammalian-based expression system.

Immunogen: Recombinant full-length human Elastin protein

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Elastin

Target: Elastin (ELN)

Andere Bezeichnung: Elastin

Hintergrund:

Elastin, ELN, SVAS, Tropoelastin, WBS, WS

Colon: A moderate to strong elastin immunostaining should be seen of fibres in the lamina propria, around smooth muscle cells of the muscularis mucosae, and in blood vessels (subendothelial).

Molekulargewicht: 70kDa

Gen-ID: 2006, 647061

UniProt: P15502

Pathways: Regulation of Actin Filament Polymerization