Rekombinanter LI Cadherin Antikörper (AA 242-418)

Produktnummer ABIN7862370

Der Kaninchen Monoklonal anti-LI Cadherin Antikörper wird verwendet zum Nachweis von LI Cadherin in Proben von Human. Er wurde validiert für WB und IHC.

Kurzübersicht für Rekombinanter LI Cadherin Antikörper (AA 242-418) (ABIN7862370)

Target: LI Cadherin

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser LI Cadherin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: CDH17-8513R

Produktdetails anti-LI Cadherin Antikörper

Bindungsspezifität: AA 242-418

Verwendungszweck: Recombinant Cadherin 17 / LI Cadherin (Gastric Adenocarcinoma Marker) Antibody

Spezifität: It recognizes a protein of 120 kDa, which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.

Aufreinigung: 200ug/ml of Ab purified from rabbit anti-serum by Protein A.

Immunogen: Recombinant fragment (around aa 242-418) of human Cadherin 17 protein (CDH17) (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu LI Cadherin

Target: LI Cadherin

Andere Bezeichnung: Cadherin 17

Hintergrund:

BILL-cadherin, Cadherin-17, CDH17, HPT-1 cadherin, human intestinal peptide-associated transporter HPT-1, human peptide transporter 1 (HPT-1), Intestinal peptide-associated transporter HPT-1, LI-cadherin (liver-intestine), Liver Cadherin, Liver-intestine cadherin

Human stomach, colon, liver or small intestine. HepG2 or HT29 cells.

Molekulargewicht: 120kDa

Gen-ID: 1015, 591853

UniProt: Q12864