VWF Antikörper

Produktnummer ABIN7864543

Der Maus Monoklonal anti-VWF Antikörper (Klon VWF-4458) (ABIN7864543) detektiert spezifisch VWF in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für VWF Antikörper (ABIN7864543)

Target: VWF (Von Willebrand Factor (VWF))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser VWF Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: VWF-4458

Produktdetails anti-VWF Antikörper

Verwendungszweck: von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) Antibody

Spezifität: Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human VWF (exact sequence is proprietary)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu VWF

Target: VWF (Von Willebrand Factor (VWF))

Andere Bezeichnung: von Willebrand Factor

Hintergrund:

Coagulation Factor VIII, Factor VIII Related Antigen, F8VWF, von Willebrand Antigen 2, von Willebrand Disease (vWD)

HUVEC cells. Human tonsil.

Molekulargewicht: 250kDa

Gen-ID: 7450, 440848

UniProt: P04275