ETS2 Antikörper

Produktnummer ABIN7862765

Der Maus Monoklonal anti-ETS2 Antikörper (Klon PCRP-ETS2-1D9) (ABIN7862765) detektiert spezifisch ETS2 in ELISA, IF und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ETS2 Antikörper (ABIN7862765)

Target: ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ETS2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: PCRP-ETS2-1D9

Produktdetails anti-ETS2 Antikörper

Verwendungszweck: ETS2 (Transcription Factor) Antibody

Spezifität: ETS2 (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. ETS2 was shown to be mutated in reeler mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. ETS2 protein expression is complex and changes throughout development. ETS2 appears to function upstream of Dab1, in a signaling pathway that controls cell positioning in the developing brain, and is also thought to be a direct effector of the neurotrophin BDNF.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human ETS2 protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu ETS2

Target: ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))

Andere Bezeichnung: ETS2

Hintergrund:

C ets 2 protein, ETS2, ETS2IT1, Oncogene ETS2, Protein C-ets-2, v ets avian erythroblastosis virus E2 oncogene homolog 2, V ets avian erythroblastosis virus E26 oncogene homolog 2

Human thymus, lung or cerebellum.

Molekulargewicht: 52kDa

Gen-ID: 2114, 644231

UniProt: P15036

Pathways: EGFR Signaling Pathway, Myometrial Relaxation and Contraction