UCHL1 Antikörper

Produktnummer ABIN7863489

Der Maus Monoklonal anti-UCHL1 Antikörper (Klon UCHL1-4558) (ABIN7863489) detektiert spezifisch UCHL1 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Meerschweinchen und Hamster.

Kurzübersicht für UCHL1 Antikörper (ABIN7863489)

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Reaktivität: Human, Ratte, Maus, Meerschweinchen, Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser UCHL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: UCHL1-4558

Produktdetails anti-UCHL1 Antikörper

Verwendungszweck: PGP9.5 / UchL1 (pan-Neuronal Marker) Antibody

Spezifität: This MAb reacts with a protein of 20-30 kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: KLH conjugated synthetic peptide selected from the 185-214 region of human UCHL1

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu UCHL1

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Andere Bezeichnung: PGP9.5

Hintergrund:

Gracile Axonal Dystrophy, Neuron Cytoplasmic Park5, Parkinson Disease 5, Protein Gene Product 9.5, Ubiquitin Carboxyl-terminal Esterase L1, Ubiquitin Carboxyl-terminal Hydrolase Isozyme L1, Ubiquitin Thioesterase L1

T98G cells. Cerebellum. Human Brain, Mouse Brain, Rat Brain, Hamster Brain or Guinea pig Brain tissue

Molekulargewicht: 20-30kDa

Gen-ID: 7345, 518731

UniProt: P09936

Pathways: Feeding Behaviour