Th-POK Antikörper

Produktnummer ABIN7863208

Dieser Maus Monoklonal Antikörper detektiert spezifisch Th-POK in FACS, IF und WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Th-POK Antikörper (ABIN7863208)

Target: Th-POK

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)

Klon: PCRP-ZBTB7B-1B6

Produktdetails

Verwendungszweck: Th-Pok / ZBTB7B Antibody

Spezifität: TH-POK (T-helper-inducing POZ/Kr ppel-like factor), also known as zinc finger protein 67 (ZFP67), zinc finger and BTB domain-containing protein 7B or Kr ppel-related zinc finger protein cKrox, is a 539 amino acid protein that contains one BTB (POZ) domain and four C2H2-type zinc fingers. Localized to the nucleus, TH-POK functions primarily as a key regulator of lineage commitment of immature T-cell precursors. Specifically, the presence of TH-POK directs positively selected thymocytes to the CD4 lineage, whereas its absence causes default development to the CD8 lineage. TH-POK also functions as a transcriptional repressor of various other genes, such as COL1A1, COL1A2 and Fibronectin.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human ZBTB7B protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Antigendetails

Target: Th-POK

Hintergrund:

cKrox, hcKrox, T helper inducing POZ/Kruppel like factor, Th-POK, ThPOK, ZBTB15, ZBTB7B, ZFP67, Zinc finger and BTB domain containing 15, Zinc finger and BTB domain containing 7B, Zinc finger protein 67 homolog, Zinc finger protein 857B, Zinc finger protein ThPOK, ZNF857B

HeLa or HepG2 cells.

Molekulargewicht: 58/80kDa

Gen-ID: 51043, 729279

UniProt: O15156