SNW1 Antikörper

Produktnummer ABIN7864444

Der Maus Monoklonal anti-SNW1 Antikörper (Klon PCRP-SNW1-2A1) (ABIN7864444) detektiert spezifisch SNW1 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für SNW1 Antikörper (ABIN7864444)

Target: SNW1 (SNW Domain Containing 1 (SNW1))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SNW1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: PCRP-SNW1-2A1

Produktdetails anti-SNW1 Antikörper

Verwendungszweck: SNW1 Antibody

Spezifität: Nuclear receptor coactivator NCOA62/SNW1 (Nuclear Protein SkiP, SKIIP ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human SNW1 protein

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu SNW1

Target: SNW1 (SNW Domain Containing 1 (SNW1))

Andere Bezeichnung: SNW1

Hintergrund:

Bx42, NCoA-62, Prp45, PRPF45, SKIIP, SKIP

HeLa or U87 cells. General nuclear expression.

Molekulargewicht: 61.49kDa

Gen-ID: 22938, 25040

UniProt: Q13573

Pathways: Retinoic Acid Receptor Signaling Pathway