PRMT7 Antikörper
Kurzübersicht für PRMT7 Antikörper (ABIN7863261)
Target
Alle PRMT7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- PRMT7 Antibody
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Spezifität
- Arginine methylation is an irreversible protein modification catalyzed by Arginine methyltransferases, such as PRMT7, which uses S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport and RNA splicing. PRMT7 has two methyltransferase domains, each containing a putative AdoMet-binding motif. The N-terminal methyltransferase domain closely resembles the catalytic core of PRMT5, and the C-terminal domain is most similar to that of PRMT1. Three PRMT7 splice variants have been identified by database analysis. PRMT7 is localized to the nucleus and cytoplasm and moderate expression is observed in adult brain and lung tissues.
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Aufreinigung
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant full-length human PRMT7 protein
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))
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Andere Bezeichnung
- PRMT7
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Hintergrund
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[Myelin basic protein]-arginine N-methyltransferase PRMT7, Histone-arginine N-methyltransferase PRMT7, KIAA1933, Protein arginine methyltransferase 7, Protein arginine N-methyltransferase 7
HeLa, MCF7 or HepG2 cells.
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Molekulargewicht
- 78.46kDa
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Gen-ID
- 54496, 640229
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UniProt
- Q9NVM4
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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