Rekombinanter OCT4 Antikörper

Produktnummer ABIN7861950

Der Kaninchen Monoklonal anti-OCT4 Antikörper wird verwendet zum Nachweis von OCT4 in Proben von Human. Er wurde validiert für WB und IHC.

Kurzübersicht für Rekombinanter OCT4 Antikörper (ABIN7861950)

Target: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser OCT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: OCT4-7347R

Produktdetails anti-OCT4 Antikörper

Verwendungszweck: Recombinant OCT-4 (POU5F1) (Germ Cell Tumor Marker) Antibody

Spezifität: OCT4 is a member of the POU family of transcription factors, involved in the regulation of pluripotency during normal development and is detectable in embryonic stem and germ cells. 79oΩOCT4 is a key regulator of self-renewal in embryonic stem cells, its expression is potentially correlated with tumorigenesis and can affect tumor recurrence or resistance to therapies. OCT4 is expressed in undifferentiated pluripotent cells, germ cells in ovary and testes. OCT4 Ab is useful in the identification of primary as well as metastatic germ cell tumors.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human OCT-4/POU5F1 protein (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu OCT4

Target: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Andere Bezeichnung: OCT-4

Hintergrund:

OCT3, OCT3A, OCT4, OCT4A, OCT-3/4, Octamer-binding protein 3, Octamer-binding protein 4, Octamer-binding transcription factor 3, octamer-binding transcription factor-3, OTF-3, OTF3, OTF4, PO5F1, POU class 5 homeobox 1, POU domain, class 5, transcription factor 1, POU-type homeodomain-containing DNA-binding protein, POU5F1

Raji or U-937 cells. Human seminoma or testicular carcinoma

Molekulargewicht: 38.6kDa

Gen-ID: 5460, 249184

UniProt: Q01860

Pathways: Stem Cell Maintenance