Rekombinanter Periostin Antikörper

Produktnummer ABIN7861905

Der Kaninchen Monoklonal anti-Periostin Antikörper wird verwendet zum Nachweis von Periostin in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Rekombinanter Periostin Antikörper (ABIN7861905)

Target: Periostin (POSTN)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Periostin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: POSTN-8951R

Produktdetails anti-Periostin Antikörper

Verwendungszweck: Recombinant Periostin (POSTN) Antibody

Spezifität: Periostin (PN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for ±V≤3 and ±V≤5 integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment, spreading and attachment. Periostin is mainly detected in lower gastrointestinal tract, aorta, stomach, placenta, uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor ≤ 1 (TGF ≤ 1). Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human POSTN protein (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Periostin

Target: Periostin (POSTN)

Andere Bezeichnung: Periostin

Hintergrund:

Fasciclin-I like, Osteoblast specific factor 2 (OSF2), PDLPOSTN, Periodontal ligament specific periostin, Periostin isoform thy2 / th4 / thy6 / thy8, Periostin osteoblast specific factor, PN, POSTN

breast or colon tissue.|Human placenta

Molekulargewicht: 84/74kDa (Periostin), 90kDa (secreted glycoprotein)

Gen-ID: 10631, 136348, 721018

UniProt: Q15063