Rekombinanter NME2 Antikörper

Produktnummer ABIN7861870

Der Kaninchen Monoklonal anti-NME2 Antikörper (Klon NME2-12953R) (ABIN7861870) detektiert spezifisch NME2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter NME2 Antikörper (ABIN7861870)

Target: NME2 (Nucleoside diphosphate kinase B (NME2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser NME2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: NME2-12953R

Produktdetails anti-NME2 Antikörper

Verwendungszweck: Recombinant NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) Antibody

Spezifität: The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human NME2 protein

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu NME2

Target: NME2 (Nucleoside diphosphate kinase B (NME2))

Andere Bezeichnung: NME2

Hintergrund:

C myc purine binding transcription factor PUF, C-myc purine-binding transcription factor PUF, epididymis secretory sperm binding protein Li 155an, HEL-S-155an, Histidine protein kinase NDKB, NDP kinase B, NDPKB, nm23-H2, NM23B, NME/NM23 nucleoside diphosphate kinase 2, nme2, Nucleoside diphosphate kinase B,

Ubiquitously expressed in all tissues. HeLa, MCF7

Molekulargewicht: 17kDa

Gen-ID: 4831, 463456

UniProt: P22392