NPPB Antikörper

Produktnummer ABIN7863196

Der Maus Monoklonal anti-NPPB Antikörper wird verwendet zum Nachweis von NPPB in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für NPPB Antikörper (ABIN7863196)

Target: NPPB (Natriuretic Peptide Precursor B (NPPB))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NPPB Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: NPPB-4493

Produktdetails anti-NPPB Antikörper

Verwendungszweck: Natriuretic Peptide B / NPPB Antibody

Spezifität: Natriuretic peptides comprise a family of three structurally related molecules: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP) and C-type natriuretic peptide (CNP). ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. These peptides possess potent natriuretic, diuretic and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control. ANP, BNP and CNP are highly homologous within the 17-residue ring structure formed by an intramolecular disulfide linkage. The genes which encode for ANP and BNP map to human chromosome 1p36.22. The gene which encodes for CNP maps to human chromosome 2q37.1.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human NPPB (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu NPPB

Target: NPPB (Natriuretic Peptide Precursor B (NPPB))

Andere Bezeichnung: Natriuretic Peptide B

Hintergrund:

Brain natriuretic peptide 32, Brain type natriuretic peptide, Gamma brain natriuretic peptide, Natriuretic peptide B, Natriuretic peptide precursor B, natriuretic peptide, brain type, Natriuretic peptides B, natriuretic protein, NPPB

Human heart, liver or uterus.

Molekulargewicht: 25-36kDa (glycosylated BNP precursor), 12kDa (deglycosylated mature BNP)

Gen-ID: 4879

UniProt: P16860

Pathways: Hormone Activity