LIM Domain Binding 2 Protein Antikörper

Produktnummer ABIN7861635

Der Maus Monoklonal anti-LIM Domain Binding 2 Protein Antikörper wird verwendet zum Nachweis von LIM Domain Binding 2 Protein in Proben von Human. Er wurde validiert für IHC, IF und FACS.

Kurzübersicht für LIM Domain Binding 2 Protein Antikörper (ABIN7861635)

Target: LIM Domain Binding 2 Protein (LDB2) (LIM Domain Binding 2 (LDB2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LIM Domain Binding 2 Protein Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: PCRP-LDB2-1B10

Produktdetails anti-LIM Domain Binding 2 Protein Antikörper

Verwendungszweck: LDB2 Antibody

Spezifität: The LIM-only (LMO) proteins, LMO1 and LMO2, are nuclear factors that are characterized by a conserved LIM domain. The LIM domain consists of a cysteine-rich zinc-binding motif that is present in a variety of transcription factors, including the LIM homeobox (LHX) proteins expressed in the central nervous system and involved in cell differentiation. LMO1 and LMO2 are expressed in the adult CNS in a cell type-specific manner, where they are differentially regulated by neuronal activity and are involved in regulating the cellular differentiated phenotype of neurons. LMO2 lacks a specific DNA-binding homeobox domain but rather assembles into transcriptional regulatory complexes to mediate gene expression by interacting with the widely expressed nuclear LIM interactor (NLI). NLI, known also as CLIM-1, and the related protein CLIM-2 facilitate the formation of heteromeric LIM complexes and also enhance the nuclear retention of LIM proteins. LMO2 and the related protein LMO4 are expressed in thymic precursor cells. LMO4 is also expressed in mature T cells, cranial neural crest cells, somite, dorsal limb bud mesenchyme, motor neurons, and Schwann cell progenitors.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human LDB2 protein

Isotyp: IgG2c, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu LIM Domain Binding 2 Protein

Target: LIM Domain Binding 2 Protein (LDB2) (LIM Domain Binding 2 (LDB2))

Andere Bezeichnung: LDB2

Hintergrund:

CLIM1, LDB1, LIM domain binding 2

HeLa cells.

Molekulargewicht: 42.7kDa

Gen-ID: 9079, 714330

UniProt: O43679

Pathways: Stem Cell Maintenance