Rekombinanter KRT17 Antikörper

Produktnummer ABIN7861579

Der Kaninchen Monoklonal anti-KRT17 Antikörper (Klon KRT17-8346R) (ABIN7861579) detektiert spezifisch KRT17 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter KRT17 Antikörper (ABIN7861579)

Target: KRT17 (Keratin 17 (KRT17))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser KRT17 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: KRT17-8346R

Produktdetails anti-KRT17 Antikörper

Verwendungszweck: Recombinant Cytokeratin 17 (CK17) (Basal Epithelial Marker) Antibody

Spezifität: CK17 is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glands 79oΩsuch as mammary, sweat and salivary. CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered as epithelial stem cell marker because CK17 Ab marks basal cell differentiation. CK17 is expressed in SCLC much higher than in LADC. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. Additionally, anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human KRT17 protein (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu KRT17

Target: KRT17 (Keratin 17 (KRT17))

Andere Bezeichnung: Cytokeratin 17

Hintergrund:

K17, Keratin Type I Cytoskeletal 17, Keratin-17, KRT17, PCHC1

bladder or cervix.|T24 cells. Human skin

Molekulargewicht: 46kDa

Gen-ID: 3872, 2785

UniProt: Q04695