Rekombinanter CDH6 Antikörper

Produktnummer ABIN7861568

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch CDH6 in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter CDH6 Antikörper (ABIN7861568)

Target: CDH6 (K-Cadherin (CDH6))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CDH6 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: CDH6-9300R

Produktdetails anti-CDH6 Antikörper

Verwendungszweck: Recombinant Cadherin-6 (CDH6) / K-Cadherin Antibody

Spezifität: This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion. This protein may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human Cadherin 6 protein (CDH6) (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu CDH6

Target: CDH6 (K-Cadherin (CDH6))

Andere Bezeichnung: Cadherin-6

Hintergrund:

Cadherin-6, CDH6, CAD6, KCAD,

Human kidney or renal cell carcinoma.

Molekulargewicht: 130kDa

Gen-ID: 1004, 124776

UniProt: P55285

Pathways: Cell-Cell Junction Organization