Estrogen Receptor alpha Antikörper
Kurzübersicht für Estrogen Receptor alpha Antikörper (ABIN7861284)
Target
Alle Estrogen Receptor alpha (ESR1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Estrogen Receptor, alpha (Marker of Estrogen Dependence) Antibody
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Spezifität
- This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.
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Aufreinigung
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant human Estrogen Receptor alpha protein
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Isotyp
- IgG1, kappa
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anti-Estrogen Receptor 1 (ESR1) antibody
ESR1 Reaktivität: Human WB, IHC Wirt: Maus Monoclonal ESR1-1904 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 129-312) antibodyESR1 Reaktivität: Human WB, IHC, IF, FACS Wirt: Maus Monoclonal ESR1-3557 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 246-273) antibodyESR1 Reaktivität: Human, Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB33807 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 2-185) antibodyESR1 Reaktivität: Human, Ratte WB, IHC, ELISA, FACS, ICC Wirt: Maus Monoclonal 6A6E8 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 2-185) antibodyESR1 Reaktivität: Human WB, IHC, IF, FACS Wirt: Maus Monoclonal ER506 unconjugated
anti-Estrogen Receptor 1 (ESR1) antibodyESR1 Reaktivität: Human WB, IHC, FACS, ICC, IP Wirt: Maus Monoclonal 119-13 unconjugated
anti-Estrogen Receptor 1 (ESR1) (pSer167) antibodyESR1 Reaktivität: Human, Ratte ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 233-483) antibodyESR1 Reaktivität: Maus WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 129-312) antibodyESR1 Reaktivität: Human WB, IHC, FACS Wirt: Maus Monoclonal ESR1-3559 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 331-360) antibodyESR1 Reaktivität: Human, Ratte WB, ELISA, FACS, IF (cc) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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Andere Bezeichnung
- Estrogen Receptor, alpha
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Hintergrund
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Estrogen Receptor alpha delta 4*5,6,7*/654 isoform, Estrogen Receptor alpha delta 4 +49 isoform, Nuclear receptor subfamily 3 group A member 1
MCF-7 cells. Breast or Endometrial Carcinoma.
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Molekulargewicht
- ~67kDa
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Gen-ID
- 2099, 208124
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UniProt
- P03372
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Pathways
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Target
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