Desmin Antikörper

Produktnummer ABIN7862703

Der Maus Monoklonal anti-Desmin Antikörper (Klon DES-3255) (ABIN7862703) detektiert spezifisch Desmin in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Hund, Rind (Kuh), Pferd und Cat.

Kurzübersicht für Desmin Antikörper (ABIN7862703)

Target: Desmin (DES)

Reaktivität: Human, Hund, Rind (Kuh), Pferd, Cat

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Desmin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: DES-3255

Produktdetails anti-Desmin Antikörper

Verwendungszweck: Desmin (Muscle Cell Marker) Antibody

Spezifität: Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain °™-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles.Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human desmin protein

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Desmin

Target: Desmin (DES)

Andere Bezeichnung: Desmin

Hintergrund:

CMD1I, CSM1, CSM2, DES, Intermediate filament protein

SJRH30 cells. Human uterus, small intestine or leiomyosarcoma.

Molekulargewicht: 52kDa

Gen-ID: 1674, 594952

UniProt: P17661