DC-SIGN/CD209 Antikörper

Produktnummer ABIN7862936

Der Maus Monoklonal anti-DC-SIGN/CD209 Antikörper (Klon C209-6774) (ABIN7862936) detektiert spezifisch DC-SIGN/CD209 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für DC-SIGN/CD209 Antikörper (ABIN7862936)

Target: DC-SIGN/CD209 (CD209) (CD209)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DC-SIGN/CD209 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: C209-6774

Produktdetails anti-DC-SIGN/CD209 Antikörper

Verwendungszweck: CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) Antibody

Spezifität: DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human CD209 protein fragment (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu DC-SIGN/CD209

Target: DC-SIGN/CD209 (CD209) (CD209)

Andere Bezeichnung: CD209

Hintergrund:

CD209, CDSIGN, CIRE, CLEC4L, DC-SIGN, DC-SIGN1, DCSIGN, Dendritic cell-specific ICAM-3 Grabbing Non-integrin 1, HIV GP120 Binding Protein, SIGN-R1, SIGNR5

THP-1 or HeLa cells (IF/FACS).

Molekulargewicht: 45kDa

Gen-ID: 30835, 278694

UniProt: Q9NNX6