Rekombinanter Annexin a1 Antikörper

Produktnummer ABIN7864755

Der Maus Monoklonal anti-Annexin a1 Antikörper (Klon rANXA1-9145) (ABIN7864755) detektiert spezifisch Annexin a1 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Kaninchen, Meerschweinchen und Hamster.

Kurzübersicht für Rekombinanter Annexin a1 Antikörper (ABIN7864755)

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte, Kaninchen, Meerschweinchen, Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Annexin a1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: RANXA1-9145

Produktdetails anti-Annexin a1 Antikörper

Verwendungszweck: Recombinant Annexin A1 / (Hairy Cell Leukemia Marker) Antibody

Spezifität: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human Annexin A1 protein

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu Annexin a1

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Andere Bezeichnung: Annexin A1

Hintergrund:

ANXA1, ANX1, Annexin-1, Chromobindin-9, LPC1, p35

HeLa or A549 cells. Human esophagus, placenta or prostate.

Molekulargewicht: 38kDa

Gen-ID: 301, 494173

UniProt: P04083

Pathways: Hormone Transport