Rekombinanter Parvin, beta Antikörper (N-Term)

Produktnummer ABIN7864316

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch Parvin, beta in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter Parvin, beta Antikörper (N-Term) (ABIN7864316)

Target: Parvin, beta (PARVB)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Parvin, beta Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: PARVB-8214R

Produktdetails anti-Parvin, beta Antikörper

Bindungsspezifität: AA 1-91, N-Term

Verwendungszweck: Recombinant Beta-Parvin Antibody

Spezifität: Beta-parvin, also known as affixin, is a focal adhesion protein belonging to a family of ILKbinding proteins that contain tandem calponin homolog domains. Along with Alpha-parvin, Beta-parvin is one of the most widely researched and characterized members of this family. These two proteins interact with the ILK kinase domain in a way that is mutually exclusive and regulates both the activity of the kinase and actin cytoskeleton adhesion. Studies have shown Beta-parvin to be downregulated within human breast cancer cells, and that its expression may influence the progression of breast cancer (Johnstone, 2008). Additional research indicates a critical role for Beta-parvin in the regulation of cardiac contractility when it is in complex with ILK (Hannigan, 2007).

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: N-terminal region (residues 1-91) of human b-parvin

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu Parvin, beta

Target: Parvin, beta (PARVB)

Andere Bezeichnung: Beta-Parvin

Hintergrund:

Affixin, beta-parvin, CGI-56, Parvb

HeLa cell lysate. HeLa cells. Human stomach.

Molekulargewicht: 41kDa

Gen-ID: 29780, 475074

UniProt: Q9HBI1