Cadherin pan Antikörper (C-Term)
Kurzübersicht für Cadherin pan Antikörper (C-Term) (ABIN7864595)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- C-Term
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Verwendungszweck
- Pan-Cadherin Antibody
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Spezifität
- Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxy terminal intracellular domains. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as ≤-catenin, to regulate cadherin function. Members of this family of adhesion proteins include rat cadherin K (and its human homolog, cadherin 6), R-cadherin, B-cadherin, E/P cadherin and cadherin-5.
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Aufreinigung
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant fragment of human C-terminal of Pan-Cadherin (exact sequence is proprietary)
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Isotyp
- IgG1, kappa
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anti-Cadherin Pan antibody
Reaktivität: Human WB, FACS, ICC Wirt: Kaninchen Monoclonal 23GB5050 unconjugated Recombinant Antibody
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Cadherin pan (Cadherin Pan)
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Andere Bezeichnung
- Pan-Cadherin
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Hintergrund
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Cadherin, CDH3, CDHP, 7B4 antigen, Cadherin-1, Cadherin-2, Cadherin-3, Cadherin-4, Cadherin-5, CAM 120/80, CD144, CD324, CD325, Cdh4, CDH5, CDHE, CDHN, E-cadherin, Epithelial cadherin, N-cadherin, NCAD, Neural cadherin, P-cadherin, Placental cadherin, UVO, Uvomorulin, Vascular endothelial cadherin
colon|Human heart|prostate or brain.
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Molekulargewicht
- 120 kDa
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Gen-ID
- 999, 1000, 1001
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UniProt
- P12830, P19022, P22223, P33151, P55283
Target
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