Neuropilin 1 Antikörper (AA 700-900)

Produktnummer ABIN7860594

Der Maus Monoklonal anti-Neuropilin 1 Antikörper wird verwendet zum Nachweis von Neuropilin 1 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Neuropilin 1 Antikörper (AA 700-900) (ABIN7860594)

Target: Neuropilin 1 (NRP1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Neuropilin 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: NRP1-4620

Produktdetails anti-Neuropilin 1 Antikörper

Bindungsspezifität: AA 700-900

Verwendungszweck: NRP1 / Neuropilin-1 Antibody

Spezifität: Neuropilin is a type I transmembrane receptor that has been implicated in aspects of axon growth and guidance and has been shown to act as a high affinity receptor for class III semaphorins and vascular endothelial growth factor (VEGF). A closely related protein, neuropilin-2, shares a common domain structure and signifcant homology with neuropilin and also acts as a receptor for the class III semaphorins and VEGF. Both neuropilins are involved in regulating many physiological pathways including axonal guidance and angiogenesis, however they exhibit differential expression in the adult vasculature. Neuropilin-2 is polysialylated and expressed on the surface of dendritic cells. It is also expressed by venous and lymphatic endothelium. Neuropilin is expressed predominantly by arterial endothelium.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa700-900) of human NRP1 protein (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu Neuropilin 1

Target: Neuropilin 1 (NRP1)

Andere Bezeichnung: NRP1

Hintergrund:

A5 protein, BDCA4, BLOOD DENDRITIC CELL ANTIGEN 4, CD304, Neuropilin-1, Neuropilin1, NP1, NPN1, transmembrane receptor, Vascular endothelial cell growth factor 165 receptor, VEGF165R

Human placenta|kidney or lymph node.|testis

Molekulargewicht: 130kDa

Gen-ID: 8829, 131704

UniProt: O14786

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals