Lactoferrin Antikörper (AA 614-645)

Produktnummer ABIN7863086

Der Maus Monoklonal anti-Lactoferrin Antikörper wird verwendet zum Nachweis von Lactoferrin in Proben von Human. Er wurde validiert für IHC, IF und FACS.

Kurzübersicht für Lactoferrin Antikörper (AA 614-645) (ABIN7863086)

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Lactoferrin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: LTF-4082

Produktdetails anti-Lactoferrin Antikörper

Bindungsspezifität: AA 614-645

Verwendungszweck: Lactotransferrin / Lactoferrin / LTF Antibody

Spezifität: Ferritin and transferrins manage necessary iron-binding functions for iron metabolism. Transferrins comprise a class of single-chain, two-sited, metal-binding proteins expressed throughout the fluid and cells of vertebrates. The three major types of transferrin include serotransferrin, lactotransferrin (lactoferrin) and ovotransferrin. Lactoferrin is found in milk, tears and leukocytes. It degrades an IgA1protease secreted by Haemophilus influenzae and, consequently, allows the human IgA1antibody to effectively abolish Haemophilus influenzae colonization. Lactoferrin also attenuates the pathogenic potential of Haemophilus influenzae by proteolytic degradation of the Hap adhesin. While lactoferrin may aid in the transmission of human T cell leukemiavirus type 1, it inhibits HIV-1 replication at the level of viral fusion and entry into cells. The inhibitory effects of lactoferrin on mixed lymphocyte reactions suggest that it may have the ability to sense the activation status of lymphocytes.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa614-645) of human Lactotransferrin protein (exact sequence is proprietary)

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Lactoferrin

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Andere Bezeichnung: Lactotransferrin

Hintergrund:

GIG12, Growth inhibiting protein 12, HLF2, Kaliocin 1, Lactoferrin, Lactoferroxin-C, Lactotransferrin, LF, LTF, Neutrophil lactoferrin, Talalactoferrin

Human lactating breast or prostate tissue.

Molekulargewicht: 78kDa

Gen-ID: 4057, 529517

Pathways: Transition Metal Ion Homeostasis