Rekombinanter GLN1 Antikörper (AA 50-250)

Produktnummer ABIN7860261

Der Kaninchen Monoklonal anti-GLN1 Antikörper wird verwendet zum Nachweis von GLN1 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Rekombinanter GLN1 Antikörper (AA 50-250) (ABIN7860261)

Target: GLN1 (Glutamine Synthetase (GLN1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser GLN1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: GLUL-8889R

Produktdetails anti-GLN1 Antikörper

Bindungsspezifität: AA 50-250

Verwendungszweck: Recombinant Glutamine Synthetase / GLUL Antibody

Spezifität: Glutamine synthetase (Gl Syn) forms a homo-octamer that serves as a catalyst for the amination of glutamic acid to form glutamine. This enzyme is a marker for astrocytes, which serve as the primary site of conversion of glutamic acid to glutamine in the brain. Induction of glutamine synthetase is seen upon astrocyte cell contact with neurons. Elevated expression of glutamine synthetase in glial cells has been shown to protect neurons from degeneration due to excess glutamate. Glutamine synthetase is also present in the liver and is involved in nitrogen homeostasis. Overexpression of glutamine synthetase has been shown in primary liver cancers, indicating a potential role for glutamine synthetase in hepatocyte transformation.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa 50-250) of human GLUL protein (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu GLN1

Target: GLN1 (Glutamine Synthetase (GLN1))

Andere Bezeichnung: Glutamine Synthetase

Hintergrund:

cell proliferation-inducing protein 59, GLUL, Glutamate ammonia ligase, GS, PIG43, PIG59, Glutamate decarboxylase, glutamine synthase, Glutamine synthetase, glutamine synthetase I, Proliferation inducing protein 43, GLNA, GLNS

Human brain|stomach or thyroid.

Molekulargewicht: 42kDa

Gen-ID: 2752, 518525

Pathways: Positive Regulation of Peptide Hormone Secretion