Elastase 3A Antikörper (AA 50-250)
Kurzübersicht für Elastase 3A Antikörper (AA 50-250) (ABIN7860247)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 50-250
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Verwendungszweck
- CELA3A / Chymotrypsin like elastase 3A Antibody
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Spezifität
- Elastases belong to a subfamily of serine proteases that function to catalytically hydrolyze a wide variety of proteins. Elastase-3A, also known as ELA3A or ELA3, is a 270 amino acid protein that belongs to the elastase family and acts as an alanine-specific protease. Secreted as a zymogen from the pancreas, Elastase-3A functions as a digestive enzyme in the intestine that participates in metabolic degradation pathways by preferentially cleaving proteins that have alanine residues. In addition, Elastase-3A is thought to play a role in the metabolism and transport of cholesterol molecules in the intestine. Altered expression of Elastase-3A may be associated with pancreatic ductal carcinoma, a highly fatal cancer of the pancreatic ducts
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Aufreinigung
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant fragment (around aa50-250) of human CELA3A protein (exact sequence is proprietary)
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- Elastase 3A (ELA3A)
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Andere Bezeichnung
- CELA3A
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Hintergrund
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ELA3, ELA3A
Human pancreas or pancreatic cancer.
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Molekulargewicht
- 29 kDa
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Gen-ID
- 10136
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UniProt
- P09093
Target
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