Rekombinanter Desmin Antikörper (AA 270-470)

Produktnummer ABIN7859692

Der Kaninchen Monoklonal anti-Desmin Antikörper (Klon DES-8610R) (ABIN7859692) detektiert spezifisch Desmin in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Huhn und Hamster.

Kurzübersicht für Rekombinanter Desmin Antikörper (AA 270-470) (ABIN7859692)

Target: Desmin (DES)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Ratte, Huhn, Hamster

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Desmin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: DES-8610R

Produktdetails anti-Desmin Antikörper

Bindungsspezifität: AA 270-470

Verwendungszweck: Recombinant Desmin (Muscle Cell Marker) Antibody

Spezifität: Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain ±-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. 79oΩAntibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin. 79oΩ

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa 270-470) of human DES protein (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu Desmin

Target: Desmin (DES)

Andere Bezeichnung: Desmin

Hintergrund:

CMD1I, CSM1, CSM2, DES, Intermediate filament protein

SJRH30 cells. Intestine, Human uterus or leiomyosarcoma.

Molekulargewicht: 52kDa

Gen-ID: 1674, 594952