Ki-67 Antikörper (AA 2293-2478)

Produktnummer ABIN7859584

Der Maus Monoklonal anti-Ki-67 Antikörper (Klon MKI67-6582) (ABIN7859584) detektiert spezifisch Ki-67 in IHC, WB, FACS und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Ki-67 Antikörper (AA 2293-2478) (ABIN7859584)

Target: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Ki-67 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: MKI67-6582

Produktdetails anti-Ki-67 Antikörper

Bindungsspezifität: AA 2293-2478

Verwendungszweck: Ki-67 (Proliferating Cell Marker) Antibody

Spezifität: Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations. 79oΩ

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human Ki67 protein fragment (around aa 2293-2478) (exact sequence is proprietary)

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu Ki-67

Target: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Andere Bezeichnung: Ki-67

Hintergrund:

KI-67, Ki67, KI-67 Antigen (KIA), MKI67, Proliferation related Ki-67 antigen

Any actively proliferating cells. Human skin|tonsil or lymph node.

Molekulargewicht: 345kDa and 395kDa

Gen-ID: 4288, 689823

UniProt: P46013

Pathways: Glycosaminoglycan Metabolic Process