Apolipoprotein D Antikörper (AA 21-119)

Produktnummer ABIN7862976

Der Maus Monoklonal anti-Apolipoprotein D Antikörper (Klon APOD-3414) (ABIN7862976) detektiert spezifisch Apolipoprotein D in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Apolipoprotein D Antikörper (AA 21-119) (ABIN7862976)

Target: Apolipoprotein D (APOD)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Apolipoprotein D Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: APOD-3414

Produktdetails anti-Apolipoprotein D Antikörper

Bindungsspezifität: AA 21-119

Verwendungszweck: Apolipoprotein D / APO-D Antibody

Spezifität: Lipids, such as phospholipids, triacylglycerols and cholesterol, are weakly soluble in aqueous solution and therefore are transported by circulation as components of lipoproteins. Lipoproteins are globular particles that consist of a non-polar core of triacylglycerols and cholesteryl esters surrounded by phospholipid, cholesterol and an amphiphilic coating of protein, known as apolipoproteins (apo). These complexes allow the dissolution and shuttling of their non-polar lipid components. At least nine different apolipoproteins are distributed in significant amounts in different human lipoproteins. Apolipoprotein D (apoD) is a member of the lipocalin superfamily of transporter proteins that bind small hydrophobic molecules, including arachidonic acid (AA). The ability of apoD to bind AA implicates it in pathways associated with membrane phospholipid signal transduction and metabolism. apoD expression has been shown to correlate both with cell cycle arrest and with prognosis in several types of malignancy, including central nervous system astrocytomas and medulloblastomas.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Human recombinant APOD protein fragment (around aa21-119) (exact sequence is proprietary)

Isotyp: IgG2c, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Apolipoprotein D

Target: Apolipoprotein D (APOD)

Andere Bezeichnung: Apolipoprotein D

Hintergrund:

APO-D protein

Human liver, kidney or spleen.

Molekulargewicht: 30kDa

Gen-ID: 347, 522555

UniProt: P05090

Pathways: Platelet-derived growth Factor Receptor Signaling