BTBD9 Antikörper (AA 200-400)

Produktnummer ABIN7859463

Der Maus Monoklonal anti-BTBD9 Antikörper wird verwendet zum Nachweis von BTBD9 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für BTBD9 Antikörper (AA 200-400) (ABIN7859463)

Target: BTBD9 (BTB (POZ) Domain Containing 9 (BTBD9))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BTBD9 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: BTBD9-7501

Produktdetails anti-BTBD9 Antikörper

Bindungsspezifität: AA 200-400

Verwendungszweck: BTBD9 Antibody

Spezifität: BTBD9 (BTB/POZ domain-containing protein 9) is a 612 amino acid protein that contains one BTB/POZ domain and one BACK (BTB/Kelch associated) domain. The BTB/POZ domain mediates homomeric and heteromeric POZPOZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including Bcl-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD9 may play a role in transcription regulation. Genetic variations in the gene that encodes BTBD9 have been associated with susceptibility to restless legs syndrome type 6 (RLS6), a condition characterized by an uncontrollable urge to move the legs while resting.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa200-400) of human BTBD9 protein (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu BTBD9

Target: BTBD9 (BTB (POZ) Domain Containing 9 (BTBD9))

Andere Bezeichnung: BTBD9

Hintergrund:

BTB/POZ domain-containing protein 9

Human fallopian tube|lung or lymph node.

Molekulargewicht: 69kDa

Gen-ID: 114781, 603858

UniProt: Q96Q07

Pathways: Transition Metal Ion Homeostasis