STING1 (AA 190-290) Antikörper

Produktnummer ABIN7862969

Der Maus Monoklonal anti-STING1 Antikörper (Klon STING1-7431) (ABIN7862969) detektiert spezifisch STING1 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für STING1 (AA 190-290) Antikörper (ABIN7862969)

Target: STING1

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: STING1-7431

Produktdetails

Bindungsspezifität: AA 190-290

Verwendungszweck: STING1 / TMEM173 Antibody

Spezifität: TMEM17 (transmembrane protein 173) is a 379 amino acid protein encoded by a gene mapping to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6 % of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa190-290) of human TMEM173 protein (exact sequence is proprietary)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Antigendetails

Target: STING1

Hintergrund:

Endoplasmic reticulum interferon stimulator, ERIS, hMITA, hSTING, Mediator of IRF3 activation, MITA, NET23, MPYS, Mitochondrial mediator of IRF3 activation, N terminal methionine proline tyrosine serine plasma membrane tetraspanner, Stimulator of interferon genes protein, Transmembrane protein 173

Cytoplasmic expression in several tissues including cells in respiratory tract, fallopian tube and cells in lymphoid tissues.

Molekulargewicht: 37-50kDa

Gen-ID: 340061, 379754

UniProt: Q86WV6