OVOL2 Antikörper (AA 175-275)

Produktnummer ABIN7859282

Dieser Maus Monoklonal Antikörper detektiert spezifisch OVOL2 in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für OVOL2 Antikörper (AA 175-275) (ABIN7859282)

Target: OVOL2 (Ovo-Like 2 (OVOL2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser OVOL2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: OVOL2-6776

Produktdetails anti-OVOL2 Antikörper

Bindungsspezifität: AA 175-275

Verwendungszweck: OVOL2 / CRE-Bpa Antibody

Spezifität: The ATF/CREB family consists of a series of transcription factors that function by binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB-3 and Luman), CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. These transcription factors share terminal leucine zipper dimerization and basic DNA binding domains and are highly variable in their N-termini. Although each of the ATF/ CREB proteins bind CREs in their homodimeric form, they can also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. Protein kinase A- mediated CREB phosphorylation induces association with a nuclear protein designated CBP (CREB-binding protein), which may represent a CREB coactivator. CRE-BPa is a nuclear protein that binds DNA as a homodimer but can also form a heterodimer with ATF-2 or Jun.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa175-275) of human OVOL2 protein (exact sequence is proprietary)

Isotyp: IgG2, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu OVOL2

Target: OVOL2 (Ovo-Like 2 (OVOL2))

Andere Bezeichnung: OVOL2

Hintergrund:

bA504H3.3, hOvo2, Ovo like 2, ovo-like zinc finger 2 (OVOL2), Transcription factor Ovo-like 2, Zinc finger protein 339 (ZNF339)

HeLa|U87 or K562 cells.

Molekulargewicht: 69.1kDa

Gen-ID: 58495, 437075

UniProt: Q9BRP0

Pathways: Tube Formation