FOXL1 Antikörper (AA 104-258)

Produktnummer ABIN7862814

Dieser Maus Monoklonal Antikörper detektiert spezifisch FOXL1 in WB, IHC, IF und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für FOXL1 Antikörper (AA 104-258) (ABIN7862814)

Target: FOXL1 (Forkhead Box L1 (FOXL1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FOXL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: PCRP-FOXL1-1F8

Produktdetails anti-FOXL1 Antikörper

Bindungsspezifität: AA 104-258

Verwendungszweck: FOXL1 / Forkhead Box Protein L1 (Transcription Factor) Antibody

Spezifität: FOXL1 is a 337 amino acid protein encoded by the mouse gene FOXL1. FOXL1 belongs to the forkhead family and contains one forkhead DNA-binding domain. The HNF3/forkhead family includes a large number of transcription factors that share a structurally related DNA binding domain. forkhead factors are known to play important roles both during development and in adults. FOXL1 is a winged helix transcriptional regulator expressed in the mesenchymal layer of developing and mature gastrointestinal tract. FOXL1-deficient mice exhibit various defects not only in the epithelial layer of the gastrointestinal tract but also in gut-associated lymphoid tissues. In the small intestine of FOXL1-deficient mice, the formation of Peyer's patches is affected, particularly in the caudal region. FOXL1 is a mesenchymal modifier of the Adenomatous Polyposis Coli (APC) gene products and plays a key role in gastrointestinal tumorigenesis.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa104-258) of human FOXL1 protein (exact sequence is proprietary)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu FOXL1

Target: FOXL1 (Forkhead Box L1 (FOXL1))

Andere Bezeichnung: FOXL1

Hintergrund:

FKHL10, FREAC6, JFJ-3, FKH6, FKH11, Forkhead box protein L1, Forkhead related transcription factor, FREAC7

HeLa or U87 cells.Ubiquitous tissue expression.

Molekulargewicht: 36-41kDa

Gen-ID: 2299, 87236

UniProt: Q12951