Luteinizing Hormone Antikörper (AA 100-300)

Produktnummer ABIN7859022

Der Maus Monoklonal anti-Luteinizing Hormone Antikörper wird verwendet zum Nachweis von Luteinizing Hormone in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Luteinizing Hormone Antikörper (AA 100-300) (ABIN7859022)

Target: Luteinizing Hormone (LH)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Luteinizing Hormone Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: LHCGR-7398

Produktdetails anti-Luteinizing Hormone Antikörper

Bindungsspezifität: AA 100-300

Verwendungszweck: Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR) Antibody

Spezifität: Recognizes a protein of 78-85 kDa, which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa 100-300) of human LHCGR protein (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu Luteinizing Hormone

Target: Luteinizing Hormone (LH)

Andere Bezeichnung: Luteinizing Hormone

Substanzklasse: Hormone

Hintergrund:

Gonadotropin receptor, GTHR-II, HHG, LCGR, LGR2, LH-R, LH/CG-R, LH/CGR, LHCGR, LHR, LHRHR, LSH-R, Luteinizing hormone receptor, Luteinizing hormone/choriogonadotropin receptor, Lutropin choriogonadotropic receptor, Lutropin-choriogonadotropic hormone receptor, ULG5

HepG2 or Jurkat cells. Human ovarian carcinoma.

Molekulargewicht: 78-85kDa

Gen-ID: 3973, 468490