Rekombinanter CD34 Antikörper (AA 100-300)

Produktnummer ABIN7863990

Der Maus Monoklonal anti-CD34 Antikörper wird verwendet zum Nachweis von CD34 in Proben von Human. Er wurde validiert für WB und IHC.

Kurzübersicht für Rekombinanter CD34 Antikörper (AA 100-300) (ABIN7863990)

Target: CD34

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD34 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: RHPCA1-8573

Produktdetails anti-CD34 Antikörper

Bindungsspezifität: AA 100-300

Verwendungszweck: Recombinant CD34 (Hematopoietic Stem Cell & Endothelial Marker) Antibody

Spezifität: This MAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. On the basis of differential sensitivity to degradation by specific enzymes, epitopes of monoclonal antibodies to CD34 are classified intoÇ 79oΩthree main categories, class I, class II and class III. It is a class II antibody whose epitope is resistant to neuraminidase but sensitive to glycoprotease and chymopapain.Ç 79oΩCD34 expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. It appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi s sarcoma, but with a lower specificity.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa100-300) of human HPCA1 protein (exact sequence is proprietary)

Isotyp: IgG1, lambda

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CD34

Target: CD34

Andere Bezeichnung: CD34

Hintergrund:

Hematopoietic Progenitor Cell Antigen, HPCA1, Mucosialin

Human tonsil or angiosarcoma. Heart.

Molekulargewicht: 90-110kDa

Gen-ID: 947, 374990

UniProt: P28906