Rekombinanter TPSAB1 Antikörper (AA 100-250)

Produktnummer ABIN7858969

Der Maus Monoklonal anti-TPSAB1 Antikörper (Klon rTPSAB1-1963) (ABIN7858969) detektiert spezifisch TPSAB1 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter TPSAB1 Antikörper (AA 100-250) (ABIN7858969)

Target: TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TPSAB1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: RTPSAB1-1963

Produktdetails anti-TPSAB1 Antikörper

Bindungsspezifität: AA 100-250

Verwendungszweck: Recombinant Tryptase (Mast Cell Marker) Antibody

Spezifität: Tryptases comprise a family of trypsin-like serine proteases (peptidase family S1). Tryptases are stored in mast cell secretory granules and basophils. Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Tryptases are released into the extracellular environment and are resistant to all known endogenous proteinase inhibitors. This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation. Mastocytosis is a term collectively used for a group of disorders in which there is abnormal accumulation of mast cells in one or multiple organs. Anti-tryptase, combined with anti-CD2, anti-CD25, and anti-CD117, can be useful in identifying reactive mast cell hyperplasia, myelogenous neoplasms, mast cell leukemia, and mastocytosis.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human Tryptase protein fragment (around aa 100-250) (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu TPSAB1

Target: TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

Andere Bezeichnung: Tryptase

Hintergrund:

Lung Tryptase, Mast cell alpha II Tryptase, Mast cell beta I Tryptase, Mast cell protease 7, Mast cell protease II, MCP7, Pituitary Tryptase, Skin Tryptase, TPS1, TPSAB1, TPSB1, Tryptase 1, Tryptase alpha 1, Tryptase skin

Human skin or tonsil.

Molekulargewicht: 31-36kDa

Gen-ID: 7177, 405479

UniProt: Q15661