S100P Antikörper (AA 1-95)

Produktnummer ABIN7858904

Dieser Maus Monoklonal Antikörper detektiert spezifisch S100P in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für S100P Antikörper (AA 1-95) (ABIN7858904)

Target: S100P (S100 Calcium Binding Protein P (S100P))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser S100P Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: S100P-7374

Produktdetails anti-S100P Antikörper

Bindungsspezifität: AA 1-95

Verwendungszweck: S100P / MIG9 Antibody

Spezifität: S100P is a 95-amino-acid protein and a member of the S100 family. S100P has been shown to mediate tumor growth, metastasis and invasion through the binding of Ca2+ ions, receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein and cathepsin D.S100P highly expressed in human placenta, gastrointestinal tract, and esophageal mucosa, but always negative in pancreas and liver. Overexpression of S100P has been detected in several cancers such as breast, colon, prostate, pancreatic and lung carcinomas, and the protein has been functionally implicated in carcinogenic processes. S100P could potentially serve as diagnostic marker, prognostic/predictive indicator and therapy target for different carcinomas.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-95) of human MIG9 protein (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu S100P

Target: S100P (S100 Calcium Binding Protein P (S100P))

Andere Bezeichnung: S100P

Hintergrund:

Migration inducing gene 9 (MIG9), S100E, S100 calcium binding protein P

Human pancreatic adenocarcinoma|placenta or spleen tissue.

Molekulargewicht: 10kDa

Gen-ID: 6286, 2962

UniProt: P25815

Pathways: Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteine